Sjögren's Syndrome
Autoimmune condition causing dry eyes and dry mouth, often associated with fatigue and joint pain. Specialist management improves quality of life.
Last medically reviewed by Dr Leena Das: March 2026
Sjögren's syndrome is a chronic autoimmune condition where the immune system attacks the moisture-producing glands, leading to dry eyes and dry mouth. It can also affect other parts of the body including joints, lungs, kidneys, and the nervous system.
Sjögren's syndrome affects approximately 0.5% of the UK population and is nine times more common in women than men. It can occur on its own (primary Sjögren's) or alongside another autoimmune condition such as rheumatoid arthritis or lupus (secondary Sjögren's).
Beyond dryness, common symptoms include fatigue (often debilitating), joint pain, difficulty swallowing or speaking, recurrent dental problems, skin dryness, and vaginal dryness. The condition can significantly impact quality of life.
Dr Das provides thorough assessment including clinical examination, blood tests (anti-Ro and anti-La antibodies, rheumatoid factor, immunoglobulins), Schirmer's test for tear production, and salivary gland assessment. Treatment focuses on managing symptoms, preventing complications, and monitoring for rare but important complications such as lymphoma.
Symptoms
- •Persistent dry eyes
- •Persistent dry mouth
- •Difficulty swallowing
- •Fatigue
- •Joint pain
- •Dental problems
- •Skin dryness
- •Vaginal dryness
Treatment Options
- ✓Artificial tears and eye drops
- ✓Saliva stimulants and substitutes
- ✓Hydroxychloroquine for joint pain and fatigue
- ✓Dental care and prevention
- ✓Immunosuppressive therapy when indicated
- ✓Regular monitoring
Frequently Asked Questions
How is Sjögren's syndrome diagnosed?
Diagnosis involves blood tests (anti-Ro/anti-La antibodies), Schirmer's test for tear production, and clinical assessment. Sometimes a lip biopsy is needed. Dr Das will determine the most appropriate tests.
Is Sjögren's syndrome serious?
While primarily affecting quality of life through dryness and fatigue, Sjögren's can rarely affect internal organs and carries a small increased risk of lymphoma. Regular specialist monitoring helps detect and manage any complications early.
Can Sjögren's syndrome be treated?
While there is no cure, symptoms can be effectively managed with moisture replacement, medications for fatigue and joint pain, and regular dental care. Dr Das will create a personalised management plan.
Expert Sjögren's Syndrome Care
Book a private consultation with Dr Leena Das. Self-referral accepted — no GP referral needed.
Book Appointment — From £225