Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune condition where the immune system mistakenly attacks the lining of the joints, causing inflammation, pain, swelling, and stiffness. It most commonly affects the small joints of the hands and feet but can affect any joint in the body.

RA affects approximately 1 in 100 people in the UK, with women being two to three times more likely to develop the condition than men. It typically develops between the ages of 30 and 60, though it can occur at any age.

Early symptoms of rheumatoid arthritis include joint pain and stiffness, particularly in the mornings lasting more than 30 minutes, swelling and warmth in the affected joints, fatigue, and a general feeling of being unwell. The condition often affects joints symmetrically, meaning if one hand is affected, the other usually is too.

Early diagnosis is crucial because prompt treatment can prevent irreversible joint damage. Dr Das uses a combination of clinical examination, blood tests (including rheumatoid factor and anti-CCP antibodies), and imaging (X-rays, ultrasound, or MRI) to diagnose RA accurately.

Treatment for rheumatoid arthritis typically begins with disease-modifying antirheumatic drugs (DMARDs) such as methotrexate, which slow the progression of the disease and prevent joint damage. For patients who do not respond adequately to conventional DMARDs, biologic therapies and targeted synthetic DMARDs offer highly effective alternatives. As a Principal Investigator in multiple rheumatological trials, Dr Das has extensive experience with the latest treatments, including biologics and JAK inhibitors.

Ongoing monitoring is essential in RA management. Dr Das provides regular reviews to assess disease activity, adjust medications as needed, and monitor for any side effects. The goal of treatment is to achieve remission or low disease activity, allowing patients to maintain their quality of life and continue their daily activities without limitation.